CONCERNING PSEUDOMORPHINE

Disposition and metabolism of ( 3 H)pseudomorphine in the rat.

[3H]pseudomorphine (3H-PM) was prepared by the oxidation of [3H]morphine. A method for the estimation of 3H-PM in biological materials was developed with a minima1 sensitivity of 2.5 ng/ml of biologic material. Following the subcutaneous injection of 3H-PM (10 mg/kg as free base) in rats, the levels of 3H-PM in brain and spinal cord over a 2-hr period ranged between 46 to 17.9 rig/g and 24 to 7...

Concerning Inoculation

the efficacy of that procedure in the way which had been commended, for such purposes, in my evidence to the Plague Commission of 1898-99, and in which I had been testing curative treatments in India. The experiment on that occasion was not completed by them, and although the preliminary statement which they made oil the results was favourable to the therapy, they did not persevere with the stu...

Scientific Issues concerning Androids Scientific Issues concerning Androids

In the development of humanoids, both the appearance and behavior of the robots are significant issues. However, designing the robot’s appearance, especially to give it a humanoid one, was always a role of industrial designers. To tackle the problem of appearance and behavior, two approaches are necessary: one from robotics and the other from cognitive science. The approach from robotics tries ...

Concerning Histidine and Carnosine

Our knowledge of carnosine is largely due to the admirable investigations of Gulewitsch. The discovery of the base in beef muscle extract was first reported by Gulewitsch and Amiradiib? in 1900. Later Kutsche? isolated a substance from beef muscle extract, which he named ignotine, but Gulewitscl? showed that ignotine and carnosine were identical. In the same volume, he4 showed that hydrolysis o...

Medical opinion concerning euthanasia.